生殖発生学研究室
Kato laboratory

生命環境学部 生命医科学科 加藤研究室
研究業績リスト
【原著論文(*:責任著者)】
・Shimada R, Kato Y, Takeda N, Fujimura S, Yasunaga K, Usuki S, Niwa H, Araki K, Ishiguro
K*. STRA8-RB interaction is required for timely entry of meiosis in mouse female germ cells,
Nature Communications, 14, 6443, 2023.
・Kato Y*, Saga Y. Antagonism between DDX6 and PI3K-AKT signaling is an oocyte-intrinsic
mechanism controlling primordial follicle growth, Biology of Reproduction, 109, 73-82, 2023.
・Sano H*, Nakamura A, Yamane M, Niwa H, Nishimura T, Araki K, Takemoto K, Ishiguro K,
Aoki H, Kato Y, Kojima M. The polyol pathway is an evolutionarily conserved system for
sensing glucose uptake, PLoS Biology, 20(6)e3001678, 2022.
・Shimada R, Koike H, Hirano T, Kato Y, Saga Y*. NANOS2 suppresses the cell cycle by
repressing mTORC1 activators in embryonic male germ cells, iScience, 24, 102890, 2021.
・Fukuda K, Muraoka M, Kato Y*, Saga Y*. Decoding the transcriptome of pre-granulosa cells
during the formation of primordial follicles in the mouse, Biology of Reproduction, 105, 179-191,
2021.
・Kato Y*, Iwamori T, Ninomiya Y, Kohda T, Miyashita J, Sato M, Saga Y*. ELAVL2-directed
RNA regulatory network drives the formation of quiescent primordial follicles, EMBO Reports,
20: e48251, 2019.
・Fukuda K, Masuda A, Naka T, Suzuki A, Kato Y*, Saga Y*. Requirement of the 3’-UTR-
dependent suppression of DAZL in oocytes for pre-implantation mouse development, PLoS
Genetics, 14(6): e1007436, 2018.
・Wu Q, Fukuda K, Kato Y, Zhou Z, Deng CX, Saga Y*. Sexual fate change of XX germ cells
caused by the deletion of SMAD4 and STRA8 independent of somatic sex reprogramming, PLoS
Biology, 14(9): e1002553, 2016.
・Kato Y, Katsuki T, Kokubo H, Masuda A, Saga Y*. Dazl is a target RNA suppressed by
mammalian NANOS2 in sexually differentiating male germ cells, Nature Communications,
7:11272, 2016.
・Saba R+, Kato Y+, Saga Y*. NANOS2 promotes male germ cell development independent of
meiosis suppression, Developmental Biology, 385, 32-40, 2014. (+共同筆頭著者)
・Deguchi K, Nagamatsu G, Miyachi H, Kato Y, Morita S, Kimura H, Kitano S, Hatada I, Saga Y,
Tachibana M, Shinkai Y*. Posttranscriptional regulation of histone lysine methyltransferase GLP
in embryonic male mouse germ cells, Biology of Reproduction, 88, 1-8, 2013.
・Kato Y, Nozaki M*. Distinct DNA methylation dynamics of spermatogenic cell-specific
intronless genes is associated with CpG content, PLoS One, 7(8): e43658, 2012
・Geyer CB, Saba R, Kato Y, Anderson AJ, Chappell VK, Saga Y, Eddy EM*. Rhox13 is translated14. 15. in premeiotic germ cells in male and female and is regulated by NANOS2 in the male, Biology of Reproduction, 86, 1-9, 2012
・Shoji M, Tanaka T, Hosokawa M, Reuter M, Stark A, Kato Y, Kondoh G, Okawa K, Chujo T,
Suzuki T, Hata K, Martin SL, Noce T, Kuramochi-Miyagawa S, Nakano T, Sasaki H, Pillai RS,
Nakatsuji N, Chuma S*. The TDRD9-MIWI2 complex is essential for piRNA-mediated
retrotransposon silencing in the mouse male germline, Developmental Cell, 17, 775-787, 2009.
・Kato Y, Kaneda M, Hata K, Kumaki K, Hisano M, Kohara Y, Okano M, Li E, Nozaki M, Sasaki
H*. Role of the Dnmt3 family in de novo methylation of imprinted and repetitive sequences
during male germ cell development in the mouse, Human Molecular Genetics, 16, 2272-2280,
2007.
【総説】
・平澤竜太郎, 加藤譲, 佐々木裕之, ゲノムインプリンティングの生殖細胞における確立と着床前胚における維持機構”, 蛋白質・核酸・酵素 , 52(増刊号), 2136-2141, 2007.
・佐々木裕之, 熊木健治, 小林久人, 加藤譲, 平澤竜太郎, バイサルファイト法による
DNA メチル化解析の落とし穴, 実験医学 , 25, 2191-2196, 2007.
・Kato Y, Sasaki H*. Imprinting and looping: Epigenetic marks control interactions between
regulatory elements”, BioEssays, 27, 1-4, 2005.